Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors

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TitleExploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors
Publication TypeJournal Article
Year of Publication2018
AuthorsShadrick WR, Slavish PJ, Chai SC, Waddell B, Connelly M, Low JA, Tallant C, Young BM, Bharatham N, Knapp S, Boyd VA, Morfouace M, Roussel MF, Chen T, Lee RE, R. Guy K, Shelat AA, Potter PM
JournalBioorganic & Medicinal Chemistry
Volume26
Pagination25 - 36
ISSN0968-0896
URLhttp://www.sciencedirect.com/science/article/pii/S0968089617315948
DOI10.1016/j.bmc.2017.10.042