Biologics Characterization

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Biopharmaceuticals can exhibit tremendous heterogeneity in terms of posttranslational modifications (PTMs) such as glycosylation, oxidation, deamidation, phosphorylation etc. and structural modifications. In addition to this, changes in upstream and downstream processes during recombinant production of biologics also influence structural heterogeneity. Therefore, comprehensive characterization of biologics is necessary to ensure safety and efficacy.

Services offered by the Biologics Characterization Facility are listed below: 

  • Intact Mass-Reduced/ Non-Reduced

  • Peptide mapping

  • Post translation modification

  • Disulphide linkage analysis

  • N-glycan Analysis

  • Host Cell Proteins

  • Sequence variance analysis

We are working towards making the Biologics Characterization Facility compliant to ISO standards.