High Throughput Screening

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High Throughput Screening and High Content Imaging

The high-throughput screening and imaging facility at the Centre for Cellular and Molecular Platform (C-CAMP) has been created to assist academic and industry in developing and performing high-throughput assays involving NCEs, siRNA, shRNA and dsRNA

The core also houses a cutting-edge High Content image-based platform for chemical and biology research using both live and fixed cells.


SERVICES WE OFFER

High Throughput Screening
  • Assay development and validation (Cell-based/ Biochemical)
  • siRNA screens
  • Small molecules screens
  • Proof of concept with validation

Automated Image Analysis & Annotation Platform

  • Custom ImageJ plugin dev.
  • Custom Python based analysis program dev.
  • Target Data: Hi-speed videos, Hi-res images
  • Our WebFolio
High Content Imaging
  • Cell proliferation, cell cycle analysis
  • Cell morphology and phenotype
  • Cell stress: Cytotoxicity, cell viability, apoptosis, necrosis and mitochondrial potential
  • Signal transduction and Gene expression,
  • Specifically designed assays focused on your target(s) of interest
  • Target induction, Target translocation and / or phosphorylation
  • Neurite outgrowth and angiogenesis

 

PLATFORMS AVAILABLE

  • Liquid handling platform with 96 and 384 head, integrated with multi mode reader from TECAN
  • Cellomics Arrayscan VTi(HCS) - Thermo
  • Nikon Eclipse TiE
  • Mini robot Ep Motion from Eppendorf
  • BSL-2 cell culture facility – CO2 Incubator and BOD incubator

 

LIBRARIES

RNA Libraries

  • Human genome shRNA library
  • Drosophila RNAi library

Small molecule libraries (upcoming)

  • LOPAC sigma 1280 small molecules with proven activity
  • Biomol-368 biologically & pharmacologically active molecules
  • Prestwick collection (1120 compounds of which >85% are marketed drugs)

SERVICE REQUEST FORM

LIBRARIES AVAILABLE

FACILITY POSTER

TERMS AND POLICIES

CONTACT US


SCREENING PLATFORMS

Freedom Evo 200

Thermo Cellomics array scan VTi (HCS)

Eppendorf epMotion 5070

Nikon Eclipse TiE


Contact:

For more information on High Throughput Screening and High Content Imaging, please write to services [at] ccamp.res.in or hts [at] ccamp.res.in

Technology Manager, High Throughput Screening and High Content Imaging - Dr. Shahab Uddin M S

Business Development and Project Manager, High Throughput Screening and High Content Imaging  - Mr. Shreyas.M.Burji

Ph: 080-67185052/5055

 

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AnnualTalks2015_ScreeningFacility.pdf 555.7 KB